My husband had been having trouble with his right hand for years and had used cortisone creams, etc. prescribed by a dermatologist. Any relief was only temporary & it never completely healed. Well, since using Corium 21 his hands cleared up completely. It’s remained soft and smooth for over a year even without continued use. Now we’re trying it for dry itching skin on his shins & my dry feet. Now we’re trying it for dry itching skin on his shins & my dry feet.