Updated October 28, 2026. By Corium 21.
At bedtime, wash and pat your hands dry, apply Corium 21 generously as needed, slip on clean cotton gloves and let the cream stay on overnight. Corium 21 is an aloe vera skin cream for dry skin, with certified organic aloe vera as the first ingredient. It soaks in without a greasy or oily feel.
Is aloe vera good for dry hands?
Yes. Dry hands need moisture that soaks in, and they need it often. An aloe vera cream that isn't greasy makes that easy.
Corium 21 is an aloe vera skin cream with certified organic aloe vera as its first ingredient. It also has vitamins A, B3 and E, soluble collagen, plant oils, green tea, chamomile and ginseng.
It leaves hands feeling soft and smooth. It isn't greasy, so you can pick up a pen, a phone or a wrench right after.
Why do hands get so dry?
Washing. Sometimes frequent hand washing is enough on its own. Parents of small children and nurses know this only too well.
Hand sanitizer. It dries fast, and it takes moisture with it.
One customer who washes her hands all day put it simply:
"I am a nurse and carry a sample size of Corium 21 in my pocket. My hands become so dry from multiple washings and using ... hand sanitizers. Thank you for a superior product." Gail P.
Winter. Cold air outside, heated air inside and hot water at the sink all come at once. If you live where winters are harsh, you know how the skin on your knuckles feels: tight and rough, especially after washing.
Hard work. It doesn't have to be winter. Mechanics scrub grease off with strong hand cleansers. Cleaners, painters, gardeners and builders handle soap, plaster, concrete, paint, tools and gloves all day.
What is the cotton glove night routine?
This is the easiest habit for winter hands, because you do it while you sleep.
- Wash. Wash your hands with warm water before bed.
- Pat dry. Pat them gently with a towel, leaving them just a little damp.
- Apply generously. Smooth Corium 21 over the backs of your hands, your knuckles, your fingertips and around your nails.
- Gloves on. Slip on a pair of clean cotton gloves.
- Sleep. Let the cream stay on overnight.
- Morning. Rinse your hands, or smooth any cream that's left into your skin.
Keep the jar and the gloves together on your nightstand so the routine takes a minute.
What kind of cream works well for a night routine?
A thick cream that stays where you put it, then soaks into the skin without a greasy or oily feel. Corium 21 is a cream, not a gel, with certified organic aloe vera first, plus soluble collagen, rose hip oil and vitamins A, B3 and E.
How do I use aloe vera cream on dry hands during the day?
After every wash. Pat your hands dry and smooth in Corium 21 while they are still a little damp. Apply generously as needed.
After hand sanitizer. Let it dry completely, then smooth in Corium 21.
Keep it where you wash. Put a jar with a pump by the sink. Refill smaller jars from it to keep in your bag, car or desk drawer.
Flaky, dull-looking hands usually just need moisture. If you exfoliate, moisturize right after.
Work long shifts? See hand cream for nurses or hand cream for baristas and kitchen workers. For every way to use it, read how to use aloe vera cream.
Classic or Fragrance Free?
Either one. Fragrance Free is Classic with the fragrance left out. Choose Classic if you like a scent, or Fragrance Free if you would rather skip it.
Every size has the same formula. The same jar works on your face and body too, including feet and lips.
Try Corium 21 on your hands
Free Samples send two .5 oz jars, one Classic and one Fragrance Free, for $3.95 shipping, one set per customer. Try them at bedtime and see how your hands feel in the morning.
Every full-size product carries a 90-day money-back guarantee on the product price, even if it's opened. One refund per customer. No questions asked. Just email support@corium21.com. Read our promise. Call (800) 319-5114 with any question and you will talk to a real person. Or read customer reviews.
Rough heels too? See how to use aloe vera cream on dry heels. Lips feeling dry too? See our tips for dry lips. For dry skin all over, see aloe vera cream for very dry skin.
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Questions people ask
Should I wear gloves after putting on hand cream at night?
Cotton gloves help keep the cream on your hands overnight instead of on your sheets. Apply Corium 21 generously, slip on clean cotton gloves and sleep.
What is a good hand cream for very dry hands in winter?
Corium 21 is an aloe vera skin cream with certified organic aloe vera as the first ingredient. It absorbs well, isn't greasy and comes in Fragrance Free.
How often should I put on hand cream in winter?
As needed, per the label: "Apply generously as needed." After every wash and at bedtime are the easiest times to remember.